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Healthy Brain: Scientific Studies
   
 

References for Reducing the Risk of Alzheimer's Disease

Healthy Lifestyle

  1. Martins IJ, E. Hone, JK Foster, SI Sunram-Lea, A. Gnjec, SJ Fuller, D. Nolan, SE Gandy and RN Martins. "Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease." Mol Psychiatry. Jun 20 2006.
  2. Hayden KM, PP Zandi, CG Lyketsos, AS Khachaturian, LA Bastian, G. Charoonruk , JT Tschanz, MC Norton, CF Pieper, RG Munger , JC Breitner, KA Welsh-Bohmer , Cache County Investigators. "Vascular risk factors for incident Alzheimer disease and vascular dementia: the Cache County study." Alzheimer Dis Assoc Disord. 20(2), (Apr-June 2006), 93-100.
  3. Katzman R. "Luigi Amaducci memorial award winner's paper 2003. A neurologist's view of Alzheimer's disease and dementia." Int Psychogeriatr. 16(3), (Sep 2004), 259-73.
  4. Wilson RS, DA Evans, JL Bienias, CF Mendes de Leon, JA Schneider, DA Bennett. "Proneness to psychological distress is associated with risk of Alzheimer's disease." Neurology. 61(11), (Dec 9 2003), 1479-85.
  5. Skoog I. "Vascular aspects in Alzheimer's disease." J Neural Transm Suppl. 59 (2000), 37-43.
  6. Jeong YH et al. "Chronic stress accelerates learning and memory impairments and increases amyloid deposition in APPV717I-CT100 transgenic mice, an Alzheimer's disease model." FASEB J. 20(6), (Apr 2006), 729-31.
  7. Wilson, RS, et al. "Proneness to psychological distress and risk of Alzheimer disease in a biracial community." Neurology. 64(2), (2005 Jan 25), 380-2.
  8. Scarmeas, N. et al. "Mediterranean diet and risk for Alzheimer's disease." Ann Neurol. 59(6), (2006 Jun), 912-21.
  9. Scalco MZ and R. van Reekum. "Prevention of Alzheimer disease. Encouraging evidence." Can Fam Physician. 52, (2006 Feb), 157-9, 162-4.
  10. Larson, EB et al. "Exercise is associated with reduced risk for incident dementia among persons 65years of age and older." Ann Intern Med.144(2), (2006 Jan 17),135-6. Summary for patients in: Ann Intern Med. 144(2), (2006 Jan 17), I20.
  11. Nichol KE, Parachikova AI, Cotman CW. "Three weeks of running wheel exposure improves cognitive performance in the aged Tg2576 mouse." Behav Brain Res. 2007 Dec 3;184(2):124-32. Epub 2007 Jul 10.
  12. [No authors listed] "Protecting hearts, saving minds? Cause and effect are hard to prove but research suggests that taking care of your heart may help protect your brain." Harv Health Lett. 2007 Apr;32(6):5. No abstract available.
  13. Peavy GM, Lange KL, Salmon DP, Patterson TL, Goldman S, Gamst AC, Mills PJ, Khandrika S, Galasko D. "The effects of prolonged stress and APOE genotype on memory and cortisol in older adults." Biol Psychiatry. 2007 Sep 1;62(5):472-8. Epub 2007 Jun 4.
  14. Fox KR, Stathi A, Mckenna J, Davis MG. "Physical activity and mental well-being in older people participating in Better Ageing Project." Eur J Appl Physiol. 2007Jul; 100(5):591-602. Epub 2007 Feb 7.
  15. Carvalho-Bos SS, Riemersma-van der Lek RF, Waterhouse J, Reilly T, Van Someren EJ. "Strong association of the rest-activity rhythm with well-being in demented elderly women." Am J Geriatr Psychiatry. 2007 Feb;15(2):92-100.
  16. Williams CL, Tappen RM. "Effect of exercise on mood in nursing home residents with Alzheimer's disease." Am J Alzheimers Dis Other Demen. 2007 Oct-Nov;22(5):389-97.
  17. Buchner DM. "Exercise slows functional decline in nursing home residents with Alzheimer's disease." Aust J Physiother. 2007;53(3):204. No abstract available.
  18. Hirsch C. "An exercise program led to a slower decline in activities of daily living in nursing-home patients with Alzheimer's disease." ACP J Club. 2007 Jul-Aug;147(1):5. No abstract available.
  19. Forbes DA. "An exercise programme led to a slower decline in activities of daily living in nursing home patients with Alzheimer's disease." Evid Based Nurs. 2007 Jul;10(3):89 No abstract available.
  20. Rolland Y, Pillard F, Klapouszczak A, Reynish E, Thomas D, Andrieu S, Rivière D, Vellas B. "Exercise program for nursing home residents with Alzheimer's disease: a 1-year randomized, controlled trial." J Am Geriatr Soc. 2007 Feb;55(2):158-65.
  21. Middleton LE, Kirkland SA, Maxwell CJ, Hogan DB, Rockwood K. "Exercise: a potential contributing factor to the relationship between folate and dementia." J Am Geriatr Soc. 2007 Jul;55(7):1095-8.
  22. Bousquet M, Saint-Pierre M, Julien C, Salem N Jr, Cicchetti F, Calon F. Beneficial effects of dietary omega-3 polyunsaturated fatty acid on toxin-induced neuronal degeneration in an animal model of Parkinson's disease. FASEB J. 2007 Nov 21; [Epub ahead of print]
  23. Viña J, Gomez-Cabrera MC, Borras C. Fostering antioxidant defenses: up-regulation of antioxidant genes or antioxidant supplementation? Br J Nutr. 2007 Oct;98 Suppl 1:S36-40.
  24. Levenson CW, Rich NJ. Eat less, live longer? New insights into the role of caloric restriction in the brain. Nutr Rev. 2007 Sep;65(9):412-5.
  25. Arendash GW, Jensen MT, Salem N Jr, Hussein N, Cracchiolo J, Dickson A, Leighty R, Potter H. A diet high in omega-3 fatty acids does not improve or protect cognitive performance in Alzheimer's transgenic mice. Neuroscience. 2007 Oct 26;149(2):286-302. Epub 2007 Aug 14.
  26. Scarmeas N, Luschsinger JA, Mayeux R, Stern Y.
    Mediterranean diet and Alzheimer's disease mortality.
    Neurology. 2007 Sep 11;69(11):1084-93.
  27. Galvin JE. Pass the grain; spare the brain. Neurology. 2007 Sep 11;69(11):1072-3. No abstract available.
  28. Luchsinger JA, Nobel JM, Scarmeas N. Diet and Alzheimer's disease. Curr Neurol Neurosci Rep. 2007 Sep;7(5):366-72.
  29. Lau FC, Shukitt-Hale B, Joseph JA. Nutritional intervention in brain aging: reducing the effects of inflammation and oxidative stress. Subcell Biochem. 2007;42:299-318. Review.
  30. Dosunmu R, Wu J, Basha MR, Zawia NH. Environmental and dietary risk factors in Alzheimer's disease. Expert Rev Neurother. 2007 July;7(7):887-900. Review.
  31. Pleten' AP. [A possible influence of nutrient factors in the mechanism development of the neurodegenerative diseases--alzheimers disease and spongiform encephalopathy with people] Vopr Pitan. 2007;76(2):39-44. Review. Russian.
  32. Gillette Guyonnet S, Abellan Van Kan G, Andrieu S, Barberger Gateau P, Berr C, Bonnefoy M, Dartigues JF, de Groot L, Ferry M, Galan P, Hercberg S, Jeandel C, Morris MC, Nourhashemi F, Payette H, Poulain JP, Portet F, Roussel AM, Ritz P, Rolland Y, Vellas B. IANA task force on nutrition and cognitive decline with aging. J Nutr Health Aging. 2007 Mar-Apr;11(2):132-52. Review.
  33. Lahiri DK, Maloney B, Basha MR, Ge YW, Zawia NH. How and when environmental agents and dietary factors affect the course of Alzheimer's disease: the "LEARn" model (latent early-life associated regulation) may explain the triggering of AD. Curr Alzheimer Res. 2007 Apr;4(2):219-28.
  34. Solfrizzi V, Capurso C, D'Introno A, Colacicco AM, Chirico M, Capurso A, Panza F. Whole-diet approach, Mediterranean diet, and Alzheimer disease. Arch Neurol. 2007 Apr;64(4):606; author reply 607. No abstract available.
  35. Connor WE, Connor SL. The importance of fish and docosahexaenoic acid in Alzheimer disease. Am J Clin Nutr. 2007 Apr;85(4):929-30. No abstract available.
  36. Chen CY, Jang JH, Park MH, Hwang SJ, Surh YJ, Park OJ. Attenuation of Abeta-induced apoptosis of plant extract (Saengshik) mediated by the inhibition of mitochondrial dysfunction and antioxidative effect. Ann N Y Acad Sci. 2007 Jan;1095:399-411.
  37. Devirgiliis C, Zalewski PD, Perozzi G, Murgia C. Zinc fluxes and zinc transporter genes in chronic diseases. Mutat Res. 2007 Sep 1;622(1-2):84-93. Epub 2007 Feb 17.
  38. Bourre JM. Dietary omega-3 fatty acids for women. Biomed Pharmacother. 2007 Feb-Apr;61(2-3):105-12. Epub 2007 Jan 3. Review.
  39. Ferrari CK. Functional foods and physical activities in health promotion of aging people. Maturitas. 2007 Nov 1; [Epub ahead of print]
  40. Levenson CW, Rich NJ. Eat less, live longer? New insights into the role of caloric restriction in the brain. Nutr Rev. 2007 Sep;65(9):412-5.

Protect Your Head

  1. McMurtray, A, DG Clark, D. Christine, MF Mendez. "Early-onset dementia: frequency and causes compared to late-onset dementia." Dement Geriatr Cogn Disord. 21(2), (2006), 59-64. Epub 2005 Nov 4.
  2. Blasko, I. et al. "Experimental traumatic brain injury in rats stimulates the expression, production and activity of Alzheimer's disease beta-secretase (BACE-1)."J Neural Transm.;111(4), (2004 Apr), 523-36. Epub 2004 Feb 4.
  3. Fleminger, S. et al. "Head injury as a risk factor for Alzheimer's disease: the evidence 10 years on; a partial replication." J Neurol Neurosurg Psychiatry. 74(7), (2003 Jul), 857-62.
  4. Van Den Heuvel C, Thornton E, Vink R. "Traumatic brain injury and Alzheimer’s disease: a review." Prog Brain Res. 2007;161:303-16. Review.
  5. Weber, JT. "Experimental models of repetitive brain injuries." Prog Brain Res. 2007;161-253-61. Review.
  6. Han SD, Drake AI, Cessante LM, Jak AJ, Houston WS, Delis DC, Filoteo JV, Bondi MW. "Apolipoprotein E and traumatic brain injury in a military population: evidence of a neuropsychological compensatory mechanism?" J Neurol Neurosurg Psychiatry. 2007 Oct;78(10):1103-8. Epub 2007 Feb 7.

Challenge Your Brain and Socially Active

  1. Crowe, M. et al. "Does participation in leisure activities lead to reduced risk of Alzheimer's disease? A prospective study of Swedish twins." J Gerontol B Psychol Sci Soc Sci. 58(5), (2003 Sep), P249-55.
  2. Briones TL. "Environment, physical activity, and neurogenesis: implications for prevention and treatment of Alzheimer's disease." Curr Alzheimer Res. 3(1), (2006 Feb), 49-54.
  3. Shumaker, SA., Claudine Legault, Laura H. Coker. "Behavior-based interventions to enhance cognitive functioning and independence in older adults." JAMA. 296 (2006), 2852-2854.
  4. Willis, SL., SL. Tennstedt, M. Marsiske, K. Ball, J. Elias, K. Mann Koepke, J. Morris, G. Rebok, F. Unverzagt, A. Stoddard, E. Wright. "Long-term effects of cognitive training on everyday functional outcomes in older adults." JAMA. 296 (2006), 2805-2814.
  5. Salvatierra J, Rosselli M, Acevedo A, Duara R. "Verbal fluency in bilingual Spanish/English Alzheimer's disease patients." Am J Alzheimers Dis Other Demen. 2007 Jun-Jul;22(3):190-201.
  6. Arkin, S. "Language-enriched exercise plus socialization slows cognitive decline in Alzheimer’s disease." Am J Alzheimers Dis Other Demen. 2007 Feb-Mar;22(1):67-77.
  7. Percaccio CR, Pruette AL, Mistry ST, Chen YH, Kilgard MP. "Sensory experience determines enrichment-induced plasticity in rat auditory cortex." Brain Res. 2007 Oct 12;1174:76-91. Epub 2007 Aug 9.
  8. Gammanpila UP, Burns A, Heller RF, Purandare N. "What are the benefits of cognitive enhancers for Alzheimer's Disease: use of Population Impact Measures." BMC Geriatr. 2007 Nov 6;7(1):25 [Epub ahead of print]
  9. [No authors listed] "Loneliness associated with increased risk of Alzheimer’s disease." FDA Consum. 2007 Mar-Apr;41(2):9. No abstract available.
  10. Wilson RS, Krueger KR, Arnold SE, Schneider JA, Kelly JF, Barnes LL, Tang Y, Bennet DA. "Loneliness and risk of Alzheimer’s disease." Arch Gen Psychiatry. 2007 Feb;64(2):234-40.

Aging

  1. Henderson, VW. "Cognition and cognitive aging." Climacteric. 2007 Oct; 10 Suppl 2:88-91.

Research

  1. Wenishch E, Cantegreil-Kallen I, De Rotrou, J, Garrigue P, Moulin F, Richard A, De Sant’Anna M, Rigaud AS. "Cognitive stimulation intervention for elders with mild cognitive impairment compared with normal aged subjects: preliminary results." Aging Clin Exp Res. 2007 Aug; 19(4): 316-22.
  2. Cracchiolo JR, Mori T, Nazian SJ, Tan J, Potter H, Arendash GW. "Enhanced cognitive activity – over and above social or physical activity – is required to protect Alzheimer’s mice against cognitive impairment, reduce Abeta deposition, and increase synaptic immunoreactivity." Neurobiol Learn Mem. 2007 Oct;88(3):277-94. Epub 2007 Aug 21.
  3. Ribeiro F, Guerreiro M, De Mendonça A. Verbal learning and memory deficits in Mild Cognitive Impairment. J Clin Exp Neuropsychol. 2007 Feb;29(2):187-97.
  4. Vellas B, Andrieu S, Sampaio C, Wilcook G; European Task Force Group. "Disease-modifying trials in Alzheimer’s disease: a European task force consensus." Lancet Neurol. 2007 Jan;6(1):56-62. Review.

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References for Slowing the Progression of Alzheimer's Disease

Healthy Lifestyle

  1. Riviere S., S. Gillette-Guyonnet, T. Voisin, E. Reynish, S. Andrieu, S. Lauque, A. Salva, G. Frisoni, F. Nourhashemi, M. Micas, B. Vellas. "A nutritional education program could prevent weight loss and slow cognitive decline in Alzheimer's disease." J Nutr Health Aging. 2001; 5(4): 295-9.
  2. Emerson Lombardo, A. Martin, L. Volicer, A. Mandell, X. Wen Zhang. "Comprehensive whole foods diet to reduce risk and slow progression of Alzheimer's disease." J Nutr Health Aging. 2006; 10(3): 211.
  3. Eggermont L, D. Swabb, P. Luiten, E. Scherder. "Exercise, cognition and Alzheimer's disease: more is not necessarily better." Neurosci Biobehav Rev. 2006;30(4):562-75.
  4. Logsdon RG, SM McCurry, L. Teri. "A home health care approach to exercise for persons with Alzheimer's disease." Care Manag J. 2005 Summer: 6(2): 90-7.
  5. Zhou X, Xu J, Zhao Y. "Risk factors of distress in Alzheimer's patients." Ann Acad Med Singapore. 2007 Apr;36(4):253-8.
  6. Mamhidir AG, Karlsson I, Norberg A, Mona K. "Weight increase in patients with dementia, and alteration in meal routines and meal environment after integrity promoting care." J Clin Nurs. 2007 May; 16(5):987-96.

Challenge Your Brain and Socially Active

  1. Ermini-Funfschilling D, Stahelin HB. "Is prevention of dementia possible?" [Article in German].
    Z Gerontol. 1993 Nov-Dec; 26(6):446-52.
  2. Knapp M, L. Thorgrimsen, A. Patel, A. Spector, A. Hallam, B. Woods, M. Orrell. "Cognitive stimulation therapy for people with dementia: cost-effectiveness analysis." Br J Psychiatry. 2006 Jun;188:574-80.
  3. Butler, RN, F. Forette, BS Greengross. "Maintaining cognitive health in an ageing society." J R Soc Health. 2004 May;124(3):119-21.
  4. Perry J, S. Galloway, JL Bottorff, S. Nixon. "Nurse-patient communication in dementia: improving the odds." J Gerontol Nurs. 2005 Apr;31(4):43-52.
  5. Droes RM, F. Meiland, M. Schmitz, W. van Tilburg. "Effect of combined support for people with dementia and carers versus regular day care on behaviour and mood of persons with dementia: results from a multi-centre implementation study." Int J Geriatr Psychiatry. 2004 Jul; 19(7):673-84.
  6. Colling KB. "Caregiver interventions for passive behaviors in dementia: links to the NDB model." Aging Ment Health. 2004 Mar;8(2):117-25.
  7. Synder L, Jenkins C, Joosten L. "Effectiveness of support groups for people with mild to moderate Alzheimer’s disease: an evaluative survey." Am J Alzheimers Dis Other Demen. 2007 Feb-Mar;22(1):14-9.
  8. Cohen-Mansfield J, Wirtz PW. "Characteristics of adult day care participants who enter a nursing home."
    Psychol Aging. 2007 Jun;22(2):354-60.
  9. Malaquin-Pavan E, Pierrot M. [Caring for a person affected by Alzheimer’s disease: specific aspects of grief in family caregivers and their social support]
    Rech Soins Infirm. 2007 Jun;(89):76-102. French.

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